#26: Venom
AKA: Edward "Eddie" Brock, Anti-Venom, Toxin, Captain Universe
Powers: Super strength, shoots webs, clings to walls
First Appearance: The Amazing Spider-Man #298, 1988
Created By: David Michelinie, Todd McFarlane
Portrayed By: Topher Grace, Tom Hardy
3 votes, 91 points (Top voter: Beta Metroid)
This one's a bit complicated, because we're kind of dealing with two characters here. Two of the three voters specifically cited Brock on their list, so I'm approaching this as the bond between the two. It all started when Spider-Man was on another planet, participating in the original Secret Wars event, which was developed to sell a new line of toys. Part of that was him getting a new black costume, which he got out of what was essentially an alien vending machine. The suit looked cool and created its own webbing, so Peter kept it after returning to Earth, but he discarded it once he realized it was actually an alien organism that was influencing his mind. Meanwhile, Eddie Brock was a fellow journalist with a failing career, who blamed his problems on Spider-Man. He happened to be nearby contemplating suicide when the alien symbiote found him, and the two bonded over their shared hatred of the webslinger. The symbiote gave Eddie an approximation of Spider-Man's powers, and together they became Venom.
While initially a foe of Spider-Man, it wasn't too long before they evolved into more of an anti-hero, nicknamed the Lethal Protector, wanting to do good but willing to commit great violence to achieve it. Eventually they returned to outright villainy, but then Eddie and the symbiote parted ways. Eddie bonded with other symbiotes, and Venom bonded with other hosts. Over time they both returned to wanting to do good, and reunited a few years ago. Shortly thereafter, Eddie learned that all of the symbiotes were created by an evil god named Knull from the dawn of history, who intended to come and conquer Earth. In an extremely metal storyline, Venom warned the earth about the coming threat and helped fight off Knull and his hordes of alien dragons. Eddie is now connected to a hive-mind of the symbiotes and has ascended to a higher level of consciousness, and the symbiote has bonded with his son, Dylan.
I wasn't a big fan of Venom originally, and he still has kind of an off-putting X-Treme 90s edge, but starting about 10 years ago I got into the comics and ended up liking the character. It actually started with a run where the symbiote was bonded to Peter's high school bully and later rival Flash Thompson, and together they went on missions as Agent Venom. I kept reading when the symbiote returned to Eddie, and Donnie Cates' run on the book with the whole King in Black storyline is one of my favorites of the last few years. Topher Grace didn't make much impact with the character in the overstuffed Spider-Man 3, but Tom Hardy's bizarre performance and the goofy storyline in the standalone Venom movies has been quite endearing. The first one is better, because bad movies are just less fun when they're bad intentionally, but I enjoyed both of them.