All of the characters were intentionally designed so that they could be played in live action by their voice actors if they so choose. There's no reason why Noël Wells or anyone else couldn't show up as say, a bridge officer in some later live action post-PIC show.Of all the characters I think I want her reference in one of the live action shows. Just give us a throw-away line in DISCO or something about standout Orion Starfleet officers which mentions her specifically.