I like Thanatos's Pierced Butterfly early to get some nice damage buffs, then switch to Skelly's tooth late.I've been enjoying the hell out of the Switch port until I ran into the rare bug that renders your save file unplayable - apparently in order to avoid this, you need to have at least one point in all actively available upgrades in the Mirror of Night. They've submitted a patch to Nintendo but it hasn't been deployed yet, and the patch will render your unplayable files playable again. So I'm putting a pause on playing until the patch comes out.
I've made it to the Minotaur in Elysium 3 or 4 times but I die every time.
What Keepsakes do you guys prefer? I like having Athena's Keepsake right away so my first boon can be the Deflect Dash, but after I beat Tartarus I usually switch to the Spiked Collar for the extra health.